Key Points: • Tranexamic acid is an antifibrinolytic agent that has been used in variety of operations to reduce blood loss. • Post thyroidectomy haematoma can be life threatening, therefore multiple methods are used to reduce the risk of bleeding. • Tranexamic acid was given intra-operatively to 106 patients undergoing thyroid surgery. • Patients who received tranexamic acid had no return to theatre for post-operative haematoma (p=0.041). • There were no adverse events reported related to the administration of tranexamic acid.