Introduction
International continence society defined mixed urinary incontinence
(MUI) as “complaint of involuntary loss of urine associated with
urgency and also with effort or physical exertion or on sneezing or
coughing”., which include both urgency urinary incontinence (UUI) and
stress urinary incontinence (SUI) complaints. Urinary incontinence
affects social behaviors, financial burden such as using class of drugs,
rehabilitation floor muscles, and psychological suffering such as
dissatisfaction in sexual activity. Diagnosis of urinary incontinence is
based on history, physical examinations and supplemental evaluations
like dye test, cystoscopy, urodynamic study, urine analysis, urine
culture, and imaging technics. (1)
At the first, conservative treatments are performed for patient such as
biofeedback, pelvic floor muscle exercise, electrical stimulation and
drug treatment. In the second step of treatment, surgery is considered.
The surgery is usually used to address the failure of normal anatomic
support of the bladder neck and proximal urethra, and intrinsic
sphincter deficiency, meanwhile its implementation should be approached
with caution for carefully. In some cases, surgery intervention also
failed and other novel interventions should be considered. (2)
Platelet rich fibrin glue, stem cells, butolonium toxins and TVT
separately applied for treatment of patients, but this is the first time
that these mixed modalities were used for the treatment of mixed urinary
incontinence which did not respond to pharmaceutical and surgical
treatment.