Premature ventricular contractions (PVCs) originating from anterior interventricular septum is frequent and can be cured by radiofrequency catheter ablation (RFCA). Left ventricular diverticulum (LVD) often correlates with ventricular tachyarrhythmias and produces a higher risk of sudden cardiac death. Here, we report the case of a 29-year-old woman with a rare combination of PVCs originating from anterior interventricular septum and LVD who successfully received RFCA.