Background: Crimean-Congo hemorrhagic fever (CCHF) is a severe viral illness with high mortality rates. Nosocomial transmission poses a significant risk to healthcare workers (HCWs). Materials/methods: In this study, we evaluated the effectiveness of ribavirin in post-exposure prophylaxis (PEP) among HCWs with high-risk contacts. Exposures are grouped into 3 categories. The high-risk group consisted of HCWs who were directly exposed to blood or bodily fluids. We also included HCWs who participated in CPR without wearing appropriate PPE to the high-risk group. The moderate-risk group consisted of HCWs without a visible exposure to blood or bodily fluids but handled patient without appropriate PPE. Results: At least 38 HCWs had contact with the index fatal patient. None of the HCWs who had contact with the patient had appropriate PPE. Patient’s PCR and IgM were positive for CCHF. Among all known contacts, all HCWs in high and moderate risk groups (n:24) received PEP with ribavirin. No moderate or severe side effects were observed due to ribavirin. None of the HCWs developed nosocomial CCHF. Conclusions: There are still life-threatening gaps in the compliance of the HCWs to standard precautions. Ribavirin seems an effective and well tolerated agent for PEP of nosocomial CCHF.

Objective: To investigate temporal bone findings in COVID-19 Design: Retrospective study Settings: Using the database of our tertiary pandemic hospital, patients with COVID-19 infection with a positive PCR test and temporal bone tomography imaging were evaluated. Participants: 42 PCR positive COVID-19 patients with temporal bone imaging. Main outcome measures: A grading system was created to evaluate effusion in the middle ear and mastoid air cells. Also any specific sign in temporal bone imaging. Results: Patients were divided into two groups according to their chest CT findings. Group 1 had specific chest CT findings and included 26 patients, group 2 had no findings in chest CT and included 16 patients. No obvious temporal bone involvement was observed in any of the patients. Temporal bone imaging findings were compared according to a grading system and there was no difference between the groups (p=0,50). Conclusion: The SARS-CoV-2 does not affect the temporal bone. There was no sign of effusion in mastoid air cells or the middle ear or any specific sign in the temporal bone in our study group.