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Navigating the Evolving Landscape of Atopic Dermatitis: Challenges and Future Opportunities: the 4 th Davos Declaration
  • +69
  • Claudia Traidl-Hoffmann,
  • Jamie Afghani,
  • Cezmi Akdis,
  • Mubeccel Akdis,
  • Aydin Handan,
  • Katja Baerenfaller,
  • Heidrun Behrendt,
  • Thomas Bieber,
  • Paul L. Bigliardi,
  • Mei Bigliardi-Qi,
  • Charlotte Bonefeld,
  • Stefanie Bösch,
  • Marie-Charlotte Brüggen,
  • Sebastian Diemert,
  • Hans-Werner Duchna,
  • Martina Fähndrich,
  • Danielle Fehr,
  • Marc Fellmann,
  • Remo Frei,
  • Lene Garvey,
  • Raschid Gharbo,
  • Mehmet Gökkaya,
  • Karin Grando,
  • Carole Guillet,
  • Erman Güler,
  • Jan Gutermuth,
  • Nadine Herrmann,
  • DirkJan Hijnen,
  • Claudia Hülpüsch,
  • Alan Irvine,
  • Erika Jensen-Jarolim,
  • Heidi H Kong,
  • Hillel Koren,
  • Claudia Lang,
  • Roger Lauener,
  • Laura Maintz,
  • Pierre-Yves Mantel,
  • Emanual maverakis,
  • Matthias Moehrenschlager,
  • Svenja Müller,
  • Kari Nadeau,
  • Avidan U. Neumann,
  • Liam O'Mahony,
  • Fahafahantsoa Rapelanoro Rabenja,
  • Harald Renz,
  • Claudio Rhyner,
  • Ernst Rietschel,
  • Johannes Ring,
  • Caroline Roduit,
  • Mari Sasaki,
  • Mirjam Schenk,
  • Jens Schroder,
  • Dagmar Simon,
  • Hans-Uwe Simon,
  • Milena Sokolowska,
  • sonja stander,
  • Martin Steinhoff,
  • Doris Straub Piccirillo,
  • Alain Taïeb,
  • Roberto Takaoka,
  • Martin Tapparo,
  • Henrique Teixeira,
  • Jacob Thyssen,
  • Stephan Traidl,
  • Miriam Uhlmann,
  • Willem van de Veen,
  • Marianne van Hage,
  • Christian Virchow,
  • Andreas Wollenberg,
  • yasutaka mitamura,
  • Alexander Zink,
  • Peter Schmid-Grendelmeier
Claudia Traidl-Hoffmann
Universitat Augsburg Medizinische Fakultat

Corresponding Author:[email protected]

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Jamie Afghani
Universitat Augsburg Medizinische Fakultat
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Cezmi Akdis
CK-CARE AG
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Mubeccel Akdis
Universitat Zurich Schweizerisches Institut fur Allergie- und Asthmaforschung
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Aydin Handan
AbbVie Inc
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Katja Baerenfaller
Universitat Zurich Schweizerisches Institut fur Allergie- und Asthmaforschung
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Heidrun Behrendt
Technische Universität München
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Thomas Bieber
CK-CARE AG
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Paul L. Bigliardi
University of Minnesota Rochester
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Mei Bigliardi-Qi
University of Minnesota Rochester
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Charlotte Bonefeld
University of Copenhagen
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Stefanie Bösch
University Hospital of Zürich
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Marie-Charlotte Brüggen
CK-CARE AG
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Sebastian Diemert
Almirall Hermal GmbH
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Hans-Werner Duchna
CK-CARE AG
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Martina Fähndrich
LEO Pharmaceutical Products Sarath Ltd
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Danielle Fehr
CK-CARE AG
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Marc Fellmann
Pfizer Switzerland AG
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Remo Frei
CK-CARE AG
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Lene Garvey
University of Copenhagen
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Raschid Gharbo
Hochgebirgsklinik Davos AG
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Mehmet Gökkaya
Universitat Augsburg Medizinische Fakultat
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Karin Grando
CK-CARE AG
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Carole Guillet
University Hospital of Zürich
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Erman Güler
Pfizer
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Jan Gutermuth
Universitair Ziekenhuis
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Nadine Herrmann
Universitatsklinikum Bonn Klinik und Poliklinik fur Dermatologie und Allergologie
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DirkJan Hijnen
Diakonessenhuis Utrecht Zeist Doorn Locatie Utrecht
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Claudia Hülpüsch
Universitat Augsburg Medizinische Fakultat
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Alan Irvine
Trinity College Dublin
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Erika Jensen-Jarolim
Medizinische Universitat Wien Zentrum fur Pathophysiologie Infektiologie und Immunologie
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Heidi H Kong
National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institutes of Health
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Hillel Koren
Environmental Health LLC
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Claudia Lang
CK-CARE AG
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Roger Lauener
Ostschweizer Kinderspital
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Laura Maintz
Universitatsklinikum Bonn Klinik und Poliklinik fur Dermatologie und Allergologie
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Pierre-Yves Mantel
CK-CARE AG
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Emanual maverakis
University of California Davis
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Matthias Moehrenschlager
Hochgebirgsklinik Davos AG
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Svenja Müller
Universitatsklinikum Bonn Klinik und Poliklinik fur Dermatologie und Allergologie
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Kari Nadeau
Stanford University School of Medicine
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Avidan U. Neumann
Universitat Augsburg Medizinische Fakultat
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Liam O'Mahony
University College Cork
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Fahafahantsoa Rapelanoro Rabenja
Faculty of Médicine
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Harald Renz
Philipps University
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Claudio Rhyner
CK-CARE AG
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Ernst Rietschel
CK-CARE AG
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Johannes Ring
Klinikum rechts der Isar der Technischen Universitat Munchen Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein
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Caroline Roduit
Bern University Hospital
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Mari Sasaki
Universitats-Kinderspital Zurich
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Mirjam Schenk
CK-CARE AG
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Jens Schroder
Universitatsklinikum Schleswig Holstein Campus Lubeck Klinik fur Dermatologie Allergologie und Venerologie
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Dagmar Simon
Inselspital Universitatsspital Bern Universitatsklinik fur Dermatologie
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Hans-Uwe Simon
Universitat Bern Institut fur Pharmakologie
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Milena Sokolowska
CK-CARE AG
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sonja stander
University Hospital Münster
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Martin Steinhoff
Hamad Medical Corporation
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Doris Straub Piccirillo
CK-CARE AG
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Alain Taïeb
University of Bordeaux
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Roberto Takaoka
Hospital das Clínicas
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Martin Tapparo
Bencard Allergie GmbH
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Henrique Teixeira
AbbVie Inc
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Jacob Thyssen
University of Copenhagen
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Stephan Traidl
Cluster of Excellence RESIST (EXC 2155) Hannover Medical School
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Miriam Uhlmann
CK-CARE AG
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Willem van de Veen
Universitat Zurich Schweizerisches Institut fur Allergie- und Asthmaforschung
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Marianne van Hage
Karolinska Institute and Karolinska University Hospital Stockholm
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Christian Virchow
Universitatsmedizin Rostock Abteilung Pneumologie und Interdisziplinare Internistische Intensivmedizin
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Andreas Wollenberg
Ludwig-Maximilian-University
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yasutaka mitamura
Universitat Zurich Schweizerisches Institut fur Allergie- und Asthmaforschung
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Alexander Zink
Technical University of Munich
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Peter Schmid-Grendelmeier
CK-CARE AG
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Abstract

Aim: The 4th Davos Declaration, convened during the Global Allergy Forum (GAF) in Davos, aimed to elevate patient care for patients with atopic dermatitis (AD) by uniting experts and stakeholders. The forum addressed the high prevalence of AD, with a strategic focus on advancing research, treatment, and management to meet the evolving challenges in the field. Methods: This multidisciplinary forum brought together top leaders from research, clinical practice, policy, and patient advocacy to discuss the critical aspects of AD, including neuroimmunology, environmental factors, comorbidities, and breakthroughs in prevention, diagnosis, and treatment. The discussions were geared towards fostering a collaborative approach to integrate these advancements into practical, patient-centric care. Results The forum underlined the mounting burden of AD, attributing it to significant environmental and lifestyle changes. It acknowledged the progress in understanding AD and in developing targeted therapies but recognized a gap in translating these innovations into clinical practice. Emphasis was placed on the need for enhanced awareness, education, and stakeholder engagement to address this gap effectively and to consider environmental and lifestyle factors in a comprehensive disease management strategy. Conclusion: The 4th Davos Declaration marks a significant milestone in the journey to improve care for people with AD. By promoting a holistic approach that combines research, education, and clinical application, the Forum sets a roadmap for stakeholders to work together to improve patient outcomes in AD, reflecting a commitment to adapt and respond to the dynamic challenges of AD in a changing world.
24 Jan 2024Submitted to Allergy
10 Feb 2024Submission Checks Completed
10 Feb 2024Assigned to Editor
10 Feb 2024Review(s) Completed, Editorial Evaluation Pending
18 Jun 20241st Revision Received
19 Jun 2024Review(s) Completed, Editorial Evaluation Pending
04 Jul 2024Editorial Decision: Accept