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COVID-19 and Hereditary Spherocytosis: A Recipe for Hemolysis
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  • Tyler Severance,
  • Mahvish Rahim,
  • James French,
  • Richelle Baker,
  • Andrew Shriner,
  • Alka Khaitan,
  • Kathleen Overholt
Tyler Severance
Riley Hospital for Children

Corresponding Author:[email protected]

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Mahvish Rahim
Riley Hospital for Children
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James French
Riley Hospital for Children
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Richelle Baker
Riley Hospital for Children
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Andrew Shriner
Riley Hospital for Children
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Alka Khaitan
Riley Hospital for Children
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Kathleen Overholt
Riley Hospital for Children
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Abstract

Coronavirus Disease 2019 (COVID-19) is the most devastating pandemic of this century. Little is known about the impact of COVID-19 on children, especially those with underlying conditions. We describe the case of a 4-year-old with hereditary spherocytosis who was found to be positive for COVID-19 and secondary hemolytic anemia. With supportive care and transfusions, he clinically improved, and his hemoglobin stabilized. This case reminds us to remain vigilant in evaluating high risk patients for hemolysis in the face of infection. Further studies on the clinical presentation and trajectory of patients presenting with COVID-19 and underlying disease should be encouraged.
25 Jul 2020Published in Pediatric Blood & Cancer. 10.1002/pbc.28548