Analysis of clinical isolates collected from patients with VAIs
From 2013 to 2018, we collected 150 clinical isolates from patients with
VAIs—including
AVG- and TCC-related infections—undergoing hemodialysis in our
institution (Figure 1). To investigate the prevalence of different
species of bacterial infections across time, we divided the study period
into two intervals: (1) from 2013 to 2014 and (2) from 2015 to 2018. The
total number of collected isolates decreased in the second interval;
however, the prevalence of S. aureus infection increased by
approximately 20% (Table 1). Moreover, the patients undergoing
hemodialysis were mainly infected by Gram-positive bacteria,
particularly S. aureus , S. argenteus , and CoNS. P.
aeruginosa and BCC species were the main Gram-negative bacteria causing
VAIs in our institution.
Regarding species isolation according to VAI types,Staphylococcus spp. were mostly isolated from AVG-related
infections, whereas BCC species were mainly isolated from TCC-related
infections.