3.4 ROC based cut-off for TN and outcomes
ROC curves were used to derive at an optimal cut-off for TN which is best prognostic of outcomes, both EFS and OS separately in this whole cohort, localized and metastatic cohort separately. A cut-off of 85.5%TN for EFS and 83.5%TN for OS was derived for the whole cohort and localized cohort. For metastatic cohort, a cut-off of 84.5%TN was best prognostic for EFS. Details in Fig. 3.