3.5.2 Norovirus
The species Norwalk virus , genus Norovirus , is separated into 10 genogroups that are further classified into genotypes. In humans, norovirus infections by genogroups GI, GII, GIV and GVIII result in gastroenteritis in 50% of cases, whereas nearly all feline norovirus infections have been detected in cats with diarrhoea and belong to genogroups GIV and GVI (Di Martino et al., 2019; Patel et al., 2008). We detected feline norovirus RNA in 1/23 FPV-cases and 1/36 healthy control cats (Table 1) (p=1, Figure 2), both in genogroup GIV (Figure 6). The FPV-case library (cat #FPV202) contained a complete genome. The nine feline norovirus contigs isolated from the healthy control library (cat #CPS73) were 310 to 1927bp in length and contained sections of the polyprotein, capsid protein and VP3 regions.