Conclusion:
Adenoid cystic carcinoma is a malignant tumor characterized by features such as slow growth, high infiltration potential, and hematogenous distant metastasis. Minor salivary grand AdCCs should receive aggressive treatment to achieve negative surgical margins to inhibit recurrence. In this article, two cases of adenoid cystic carcinomas having occurred in the buccal mucosa were reported. For both cases, long-term follow-ups were carried out, which are essential for monitoring signs of recurrence or distant metastasis.