Abbreviations
ADCC: antibody-dependent cell-mediated cytotoxicity; AHR: airway hyperresponsiveness A kinase: cAMP-dependent protein kinase; ANOVA: analysis of variance; ASM: airway smooth muscle; cAMP: cyclic adenosine monophosphate; CRC: concentration-response curves; ECn: concentration inducing n% Emax; EFn: frequency inducing n% Emax; Emax: maximal effect; EFS: electrical field stimulation; FEV1: forced expiratory volume in 1st second; FRC: frequency-response curves; GINA: Global Initiative for asthma; IC50: half maximal inhibitory concentration; IgE: immunoglobulin E; IL-5: interleukin-5; IL-5Rα: IL-5 receptor α; KH: Krebs-Henseleit buffer solution; LAMA: long-acting muscarinic antagonist mAb: monoclonal antibody; MBP: major basic protein; NK cells: natural killer cells; PK: pharmacokinetic; QS: quick stretch; SEM: standard error of the mean; Th2:T-helper type 2.