Ethics approval and consent to participate
Ethical approval (R.S. 37/20, 2020; Independent Ethical Committee, Fondazione PTV Policlinico Tor Vergata) and informed consent were consistent with the National Committee of Bioethics and Committee for Bio-safety, Biotechnology and Life Sciences (available at: http://old.iss.it/binary/eric/cont/Informed_consent.pdf), the recommendations on the collection of biological samples for research purposes (available at: https://search.coe.int/cm/Pages/result_details.aspx?ObjectID=09000016805d84f0), the ethical and legal recommendations concerning the biobank and the research biorepository (available at: https://www.oeci.eu/Documents/OECI_Biobank.pdf), and the Comitato Nazionale per la Biosicurezza, le Biotecnologie e le Scienze per la Vita (Raccolta di campioni biologici a fini di ricerca, consenso informato, 2009; available at:http://bioetica.governo.it/media/3457/p2009-misto-2-raccolta-di-campioni-biologici-a-fini-di-ricerca-consenso-informato-it.pdf).