Study 3. Effect of benralizumab and mepolizumab on the FRC
to EFS
FRCs to EFS1-50Hz were generated in isolated airways.
Each EFS was delivered after that the contractile response induced by
the previous EFS was terminated, usually in 3-5 min. Experiments were
performed in C- and C+ tissues, and in passively sensitized airways that
were incubated overnight with different concentrations of either
benralizumab or mepolizumab during the sensitizing procedure.