The nucleation mechanism of the hydrate is still not fully understood and is a challenge to the hydrate evaluation. We synthesized the low consolidated hydrate bearing sediments by the tetrahydrofuran (THF) and water, and monitored the nucleation process of THF hydrate using the two dimensional longitudinal relaxation-transversal relaxation (T1-T2) nuclear magnetic resonance (NMR) method. It is observed that the nucleation rate of the right peak is higher than the left peak at low THF hydrate concentration, while is opposite when the THF hydrate concentration is high, revealing that the hydrate forms preferentially in larger pores and then forms gradually in smaller pores. In addition, ratio of longitudinal relaxation time to transversal relaxation time (T1/T2) of the left peak is increased with the increase of hydrate concentration, while the right peak remains unchanged, indicating that hydrate saturation can be estimated by T1/T2.