On 14 October 2023, an annular eclipse took place between 1503 UT and 2055 UT. It affected both North and South America. In this study, we used multiple ground-based and space-borne instruments, and we analysed ionospheric, thermospheric, magnetic and electrodynamic responses to this eclipse. In the vertical total electron content (VTEC) maps, at mid-latitudes, we observed a 40% depletion shortly after the Moon's shadow arrival. When the eclipse reached the low latitude region and the northern crest of the equatorial anomaly, we observed only 20-25% VTEC decrease in the vicinity of the eclipse path. However, after the Moon shadow crossed the magnetic equator, the low-latitude VTEC depletion reached 40%. The latter can be explained by the eclipse weakening the equatorial electric fields and, consequently, the equatorial fountain. In the topside VTEC and in the in-situ electron density measurements from Swarm B and C satellites we observed 40-50% decrease over the area affected by the eclipse. In the thermosphere, the eclipse produced a noticeable drop in the neutral mass density (7-18%) at 490-510 km of altitude, and changed the thermospheric composition in the vicinity of the eclipse path by 25-35%. Finally, the eclipse also clearly affected the geomagnetic field, especially at low and equatorial latitudes. Shortly after the umbra's arrival, we observed a clear decline in the total intensity F and the horizontal component H at all equatorial stations in South America. Whereas, in the variations of the vertical magnetic component Z no common pattern was observed during the eclipse. Key points:  the eclipse caused 40% depletion in total electron content, and it produced 40-50% decrease in electron density in the topside ionosphere  satellites show 7 to 20% decrease in the neutral mass density and 25-35% change in the thermospheric composition due to the eclipse  magnetic measurements show a clear decrease in the total intensity and horizontal component at low latitudes during the eclipse