Abstract
This paper studies some deterministic mathematical models that seek to
explain the expansion of Zika virus, as a viral epidemic, using
published data for Brazil. Three SIR type models considering several
aspects in the spread of the disease are considered with 3, 6 and 10
unknown parameters respectively. The parameter identification is carried
through a search algorithm based on a combination of a stochastic domain
exploration and a heuristic calculation of a descent direction, in order
to avoid stopping the algorithm at a local optimum. The models are
validated using the epidemic data found. Finally, it was confirmed that
the basic reproductive ratio ℜ 0 is consistent with those previously
reported in the literature. We conclude that the proposed optimization
method improves computation time with respect to a genetic algorithm or
an exhaustive search in the parameter space.