The impact of high Glycated Hemoglobin A1c on prognosis in patients with
Bell’s palsy:A propensity score-matched analysis
- Erhui Yu,
- Binyan Yu,
- Fanyuan Jin,
- Huafeng Cai,
- Jinhua Hu,
- Yingtong Chen,
- Runcheng Wang,
- Xiuzhen Xie,
- Shuhan Yang,
- Lihua Xuan
Erhui Yu
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileBinyan Yu
The First Affiliated Hospital of Zhejiang Chinese Medical University
Author ProfileFanyuan Jin
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileHuafeng Cai
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileJinhua Hu
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileYingtong Chen
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileRuncheng Wang
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileXiuzhen Xie
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileShuhan Yang
Zhejiang Chinese Medical University First Clinical Medical College
Author ProfileAbstract
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Objective: Investigate the impact of high glycated hemoglobin
A1c (HbA1c) on Bell’s palsy(BP) prognosis, adjusting for confounders
like age and Body Mass Index(BMI). Design: A retrospective
propensity score-matched study. Setting: University-affiliated
teaching hospital. Participants: 3251 patients diagnosed with
BP and admitted to Hospital of from May 4, 2018, to May 9, 2023, were
included. After propensity score matching (PSM),patients were
categorized into 103 individuals with HbA1c≥6.5% and 103 individuals
with HbA1c<6.5%. Outcomes: Evaluated demographical,
clinical characteristics and facial dysfunction severity before and
after PSM. Results: High HbA1c patients were older
(P<0.001), had higher BMI (P<0.001), and less frequently
suffered dysgeusia (P<0.001) and more often had hypertension
(P<0.001). Age had the greatest influence on HbA1c levels (95%
CI=0.748-0.803, P<0.001). Post-matching, no significant
differences in age or other factors (P>0.05). Initial
House-Brackmann grade (H-B grade) showed no statistical difference
(P=0.06), but final H-B grade did (P=0.002), indicating worse prognosis
for high HbA1c patients. Conclusions: After controlling for
age, BMI, dysgeusia, and hypertension, high HbA1c levels were associated
with an unfavorable outcome for Bell’s palsy patients.