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Real-world battery longevity of Implantable Loop Recorders implanted for Unexplained Syncope: results from a large single center registry
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  • L. Duvillier,
  • A. Demolder,
  • S. Van Renterghem,
  • C. De Mey,
  • F. West,
  • Jan De Pooter
L. Duvillier
Universitair Ziekenhuis Gent Hartcentrum

Corresponding Author:[email protected]

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A. Demolder
Universitair Ziekenhuis Gent Hartcentrum
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S. Van Renterghem
Universitair Ziekenhuis Gent Hartcentrum
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C. De Mey
Universitair Ziekenhuis Gent Hartcentrum
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F. West
Universitair Ziekenhuis Gent Hartcentrum
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Jan De Pooter
Universitair Ziekenhuis Gent Hartcentrum
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Abstract

Background/Purpose Implantable loop recorders (ILR) are increasingly used in cardiac rhythm monitoring and diagnostic work-up of unexplained syncope. ILR battery longevity according to manufacturers’ product performance specifications typically ranges between two to four years, but real-world data in this population are lacking. Methods This monocentric, prospective, observational study included consecutive patients with unexplained syncope undergoing ILR implantation between 10/2007 and 10/2019 The main purpose was to determine real-world battery longevity of ILR. Diagnostic yield and relationship between arrhythmogenic diagnosis and duration of ILR-monitoring was explored. Results The study included 309 patients (59 years [38-73], 49% female) with ILR implantation for unexplained syncope. Median battery longevity was 42 [40-45] months. 99.5% of ILR reached prespecified battery longevity. The time to end-of-life varied by up to 33 months among the same ILR models. Overall arrhythmogenic diagnostic yield counted 27% (73% sick sinus syndrome, 20% atrioventricular block and 7% ventricular tachycardia). Median time to diagnosis was 10 [2-25] months, with the latest event at 43 months. The cumulative diagnostic yield for arrhythmogenic event was 15.7%, 22.9%, 34.9% , 54.2%, 72.3% and 100% at 1, 2, 6, 12, 24 and 48 months respectively. In univariate analysis, 1 st degree AV-block and prolonged HV time on EP study were predictors of diagnosis, while QRS duration abnormality borderline missed significance. Conclusions Real-world battery longevity of ILRs matched industry projected longevity in 99.5% of patients implanted with ILR for unexplained syncope. A battery longevity of minimum 3.5 years is recommended to maximize the diagnostic yield in this population.
Submitted to Journal of Cardiovascular Electrophysiology
Submission Checks Completed
Assigned to Editor
Reviewer(s) Assigned
24 Jun 2024Reviewer(s) Assigned
30 Jul 2024Review(s) Completed, Editorial Evaluation Pending
01 Aug 2024Editorial Decision: Revise Minor
12 Aug 20241st Revision Received
13 Aug 2024Review(s) Completed, Editorial Evaluation Pending
13 Aug 2024Submission Checks Completed
13 Aug 2024Assigned to Editor
13 Aug 2024Reviewer(s) Assigned
20 Aug 2024Editorial Decision: Accept