A Retrospective Review on the Histopathological Pattern of Childhood
Malignant Solid Tumors in Ethiopia.
In low- and middle-income countries, malignancies remain underreported
due to lack of quality data. This study outlines the histopathological
pattern of pediatric solid malignancies in children aged 0-15yrs at the
largest referral hospital in Ethiopia. 432 solid malignancies were
evaluated. The most common malignancies were Lymphoma (21.8%),
Retinoblastoma (19.4%), and Wilms tumor (13.9%). Burkitt lymphoma
accounted for 2.1%, despite being the most reported pediatric
malignancy in sub-Saharan Africa in published literature. Definitive
diagnosis could not be made in 7% of cases, related to the lack of
confirmatory testing. The study highlights the need for improvements in
diagnostic capabilities in LMIC.