loading page

Disordered Eating in Adolescents and Young Adults with Cystic Fibrosis
  • +5
  • Alexandra Kass,
  • Laura Berbert,
  • Suzanne Dahlberg,
  • Elana Bern,
  • Sabina Sabharwal,
  • Jessica Leonard,
  • Tracy Richmond,
  • Gregory Sawicki
Alexandra Kass
Columbia University Irving Medical Center

Corresponding Author:[email protected]

Author Profile
Laura Berbert
Boston Children's Hospital
Author Profile
Suzanne Dahlberg
Boston Children's Hospital
Author Profile
Elana Bern
Boston Children's Hospital
Author Profile
Sabina Sabharwal
Children's Hospital Boston
Author Profile
Jessica Leonard
Children's Hospital Boston
Author Profile
Tracy Richmond
Children's Hospital Boston
Author Profile
Gregory Sawicki
Children's Hospital Boston
Author Profile

Abstract

Introduction: There is evidence for increased risk of eating disorders in individuals with diet-treated chronic illnesses, however, data in patients with Cystic Fibrosis (CF) is less clear. No studies have evaluated avoidant/restrictive food intake disorder (ARFID) in the CF population. We investigated the prevalence of disordered eating, including ARFID, in adolescents and young adults with CF. Methods: Patients with CF aged 14-35 years were recruited to complete three validated surveys: (1)Eating Disorder Examination Questionnaire (EDE-Q), (2)Nine-Item Avoidant/Restrictive Food Intake Disorder Scale (NIAS), and (3)Cystic Fibrosis Questionnaire-Revised (CFQ-R). Univariate linear regression analysis identified baseline risk factors associated with these survey scores. Variables with univariate p<0.20 were considered for inclusion in a multivariable linear regression model. Backwards stepwise linear regression was used to identify the final model. Results: A total of 52 patients enrolled. The prevalence of eating disorder measured on the EDE-Q was 9.6%, and on the NIAS was 13.5%. The CFQ-R eating and weight subscales were associated with scores on the EDE-Q, and CFQ-R eating subscale and being dF508 homozygous were correlated with the NIAS total score. Discussion: A clinically significant number of participants screened positive for disordered eating on the EDE-Q and NIAS. Scores on the eating and weight scales of the CFQ-R were associated with the scores on these surveys. Further work is needed to better understand the optimal way to use such tools to screen and treat for eating disorders in individuals with CF.
05 Feb 2022Submitted to Pediatric Pulmonology
07 Feb 2022Submission Checks Completed
07 Feb 2022Assigned to Editor
10 Feb 2022Reviewer(s) Assigned
28 Mar 2022Review(s) Completed, Editorial Evaluation Pending
29 Mar 2022Editorial Decision: Revise Major
22 Jun 20221st Revision Received
24 Jun 2022Submission Checks Completed
24 Jun 2022Assigned to Editor
24 Jun 2022Reviewer(s) Assigned
03 Aug 2022Review(s) Completed, Editorial Evaluation Pending
03 Aug 2022Editorial Decision: Accept