Sequential administration of anti-VEGF therapy after craniospinal irradiation and intrathecal chemotherapy for the treatment of central nervous system AML relapse after allo-HSCT: a case report and literature review

Hanyu Cao; Tao Tao; Xiang-Dong Shen; Lian Bai; Chao-Ling Wan; De-Pei Wu; Jin-Li Li; Shengli Xue

doi:10.22541/au.164027717.72466583/v1

loading page

Sequential administration of anti-VEGF therapy after craniospinal irradiation and intrathecal chemotherapy for the treatment of central nervous system AML relapse after allo-HSCT: a case report and literature review

Hanyu Cao,
Tao Tao,
Xiang-Dong Shen,
Lian Bai,
Chao-Ling Wan,
De-Pei Wu,
Jin-Li Li,
Shengli Xue

Abstract

There have been few reports on the treatment of central nervous system (CNS) acute myeloid leukemia (AML) relapse. This case study demonstrates that bevacizumab may be a viable treatment option when combined with IT chemotherapy as maintenance therapy for those with CNS leukemia.

12 Dec 2021Submitted to Clinical Case Reports

Show details

Hide details

13 Dec 2021Submission Checks Completed

13 Dec 2021Assigned to Editor

23 Dec 2021Reviewer(s) Assigned

04 Jan 2022Review(s) Completed, Editorial Evaluation Pending

05 Jan 2022Editorial Decision: Revise Minor

11 Jan 20221st Revision Received

12 Jan 2022Submission Checks Completed

12 Jan 2022Assigned to Editor

12 Jan 2022Review(s) Completed, Editorial Evaluation Pending

18 Jan 2022Editorial Decision: Accept

Abstract

Peer review status:ACCEPTED