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Tocilizumab for treating severe COVID-19 pneumonia refractory to combined hydroxychloroquine, lopinavir plus ritonavir and favipiravir: case series
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  • Manoon Surabotsophon,
  • Yingyot Klai-On,
  • Vipa Thanachartwet,
  • Sirote Khunapornphairote,
  • Supat Chamnanchanunt,
  • Theerapat Racharak,
  • Wannada Laisuan,
  • Duangjai Sahassananda,
  • Samlee Hapunna,
  • Somjit Jinapuk,
  • Suthee Leelasetakul,
  • Varunee Desakorn
Manoon Surabotsophon
Ramkhamhaeng Hospital plc

Corresponding Author:[email protected]

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Yingyot Klai-On
Ramkhamhaeng Hospital plc
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Vipa Thanachartwet
Mahidol University Rajvithi Campus
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Sirote Khunapornphairote
Ramkhamhaeng Hospital plc
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Supat Chamnanchanunt
Mahidol University Rajvithi Campus
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Theerapat Racharak
Ramkhamhaeng Hospital plc
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Wannada Laisuan
Mahidol University Faculty of Medicine Ramathibodi Hospital
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Duangjai Sahassananda
Mahidol University Rajvithi Campus
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Samlee Hapunna
Ramkhamhaeng Hospital plc
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Somjit Jinapuk
Ramkhamhaeng Hospital plc
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Suthee Leelasetakul
Ramkhamhaeng Hospital plc
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Varunee Desakorn
Mahidol University Rajvithi Campus
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Abstract

Three patients with COVID-19 pneumonia received treatment with hydroxychloroquine combined with lopinavir plus ritonavir and favipiravir. Two patients early diagnosed with COVID-19 pneumonia received tocilizumab at severe pneumonia diagnosed and survived. The third patient was late diagnosed and received tocilizumab when the disease progressed to ARDS, and passed away.
17 Jul 2020Submitted to Clinical Case Reports
20 Jul 2020Submission Checks Completed
20 Jul 2020Assigned to Editor
23 Jul 2020Reviewer(s) Assigned
30 Jul 2020Review(s) Completed, Editorial Evaluation Pending
30 Jul 2020Editorial Decision: Revise Minor
04 Sep 20201st Revision Received
05 Sep 2020Submission Checks Completed
05 Sep 2020Assigned to Editor
05 Sep 2020Review(s) Completed, Editorial Evaluation Pending
08 Sep 2020Editorial Decision: Accept
13 Oct 2020Published in Clinical Case Reports. 10.1002/ccr3.3407